Training Faculty for Biophysics, Structural Biology and Biomathematics (BSBB)

Program Directors: Roberto Sanchez, Ph.D. and Roman Osman, Ph.D.
Steering Committee: Marianna Max, Ph.D. and Mihaly Mezei, Ph.D.

This program aims to provide training in quantitative approaches to problems in biology and biomedical sciences, based on the methods of the physical and mathematical sciences. It will provide opportunities for the conceptual, methodological and practical foundations needed for research careers in modern biophysics, structural biology, and biomathematics.

Training Faculty

• Aneel Aggarwal, Ph.D., Professor, Department of Structural and Chemical Biology
  Type(s) of Research: Basic Science Research
  Research: X-ray crystallography studies of DNA/RNA binding proteins
  
• David F. Bishop, Ph.D., Professor, Department of Genetics and Genomic Sciences
  Type(s) of Research: Basic Science Research; Translational Research
  Research: Heme biosynthesis; biochemical and molecular genetics; enzymology, sequencing, genotyping and bioinformatics
  
• Oscar A. Candia, M.D., Professor, Department of Ophthalmology
  Type(s) of Research: Basic Science Research
  Research: Electrophysiology; ion channels and transporters; membrane transporters
  
• Simon Daefler, M.D., Ph.D., Assistant Professor, Department of Medicine (Infectious Diseases)
  Type(s) of Research: Basic Science Research
  Research: Cell and system biology of host-pathogen interactions in infections with intracellular bacterial pathogens
  
• Zahi A. Fayad, Ph.D., Professor, Department of Radiology
  Type(s) of Research: Basic Science Research
  Research: Using magnetic resonance imaging to study cardiovascular development and degeneration
  
• Basil G. Hanss, Ph.D., Assistant Professor, Department of Medicine
  Type(s) of Research: Basic Science Research
  Research: Mechanisms of plasma membrane nucleic acid transport
  
• Ehud Kaplan, Ph.D., Professor, Department of Neuroscience
  Type(s) of Research: Basic Science Research
  Research: Neurophysiology; visual neuroscience
  
• Derek LeRoith, M.D., Ph.D., Chief, Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine (Endocrinology)
  Type(s) of Research: Basic Science Research; Translational Research
  Research: The role of insulin and the insulin-like growth factors in pathological states including diabetes, growth, bone disorders and cancer.
  
• Avi Ma'ayan, Ph.D., Assistant Professor, Department of Pharmacology and Systems Therapeutics
  Type(s) of Research: Basic Science Research
  Research: Computational systems biology, bioinformatics, graph theory application to biological networks, software engineering and artificial intelligence application to systems biology
  
• Saul Maayani, Ph.D., Professor, Department of Anesthesiology
  Research: Human blood platelets as a system for studying membrane receptors and their effectors
  
• Marianna Max, Ph.D., Assistant Professor, Department of Neuroscience
  Type(s) of Research: Basic Science Research; Translational Research
  Research: G-protein coupled receptors for sweet taste transduction.
  
• Mihaly Mezei, Ph.D., Associate Professor, Department of Structural and Chemical Biology
  Type(s) of Research: Basic Science Research
  Research: Computer simulation of aqueous systems; methodology and biomolecular applications
  
• Roman Osman, Ph.D., Professor, Department of Structural and Chemical Biology
  Type(s) of Research: Basic Science Research
  Research: Molecular theoretical biophysics of enzymatic DNA repair; alosterism and cooperativity in the blood coagulation pathway; molecular mechanism of autoimmune diseases; protein folding
  
• Roberto Sanchez, Ph.D., Assistant Professor, Department of Structural and Chemical Biology
  Type(s) of Research: Basic Science Research
  Research: Bioinformatics; computational analysis of structure and function of proteins and genomes
  
• Stuart C. Sealfon, M.D., Professor and Chair, Department of Neurology
  Type(s) of Research: Basic Science Research
  Research: Systems biology of cellular signaling specificity in response to drugs or viruses
  
• Lawrence Sirovich, Ph.D., Professor, Department of Pharmacology and Systems Therapeutics
  Type(s) of Research: Basic Science Research
  Research: Image analysis; Mathematical modeling of various biomedical problems, and in particular the mammalian visual system
  
• Cheuk Y. Tang, Ph.D., Assistant Professor, Department of Radiology
  Type(s) of Research: Basic Science Research
  Research: Neurovascular Imaging Research and Molecular Imaging: the quest for biomarkers in diagnostic imaging
  
• Rong Wang, Ph.D., Associate Professor, Department of Genetics and Genomic Sciences
  Type(s) of Research: Basic Science Research
  Research: Proteomics and biological mass spectrometry
  
• Paul M. Wassarman, Ph.D., Professor , Department of Developmental and Regenerative Biology
  Type(s) of Research: Basic Science Research
  Research: Mechanisms of fertilization in mammals
  
• Ming-Ming Zhou, Ph.D., Professor and Chair, Department of Structural and Chemical Biology
  Type(s) of Research: Basic Science Research
  Research: Structural biology of receptor signaling, histone-directed chromatin biology and gene regulation; Mechanism-based disease biology and drug discovery; Protein NMR spectroscopy, biochemistry, molecular and chemical biology