Course Director: Maria Diverse-Pierluissi, Joseph Goldfarb
E-Mail: maria.diverse@mssm.edu, joseph.goldfarb@mssm.edu
Course Description:
Time: M-F 9:00AM-10:00AM
Room: Annenberg 19-50
Start Date: January 26, 2009.
Course Description: This course presents an overview of the basic concepts of pharmacology and drug design. The first set of lectures and conferences (15-20 hrs) deal with principles of pharmacology relevant to all drugs including absorption, distribution, metabolism, excretion, pharmacokinetics, pharmacodynamics and targets of drug action. The second part of the course will integrate the lectures of the medical school pharmacology course on cardiovascular and renal
drugs with discussion forums and web-based problem sets.
Goals and objectives:
This course is designed to teach graduate students the principles underlying the interactions between drugs, toxins, hormones, and transmitters and living organisms, including: 1) principles of
pharmacodynamics and 2) principles of pharmacokinetics such as: absorption, distribution, excretion, elimination and iotransformation, with special emphasis on metabolism by cytochromes P450, and 3) how to analyze the mechanism of action of a drug based on the target.
Format:
A combination of didactic lectures and group-based discussions will be used. Every unit of concepts will be followed by a 2-hour discussion session. The purpose of this discussion session will be to integrate the concepts discussed in class. Every discussion session will have a two components, :a clinical research paper or a case study and a basic science paper or a problem set.
Evaluation:
Discussion forum: The papers and questions will be posted in WedEd a week prior to the discussion session and the students will be asked to post their answers by the day before the session.
Take-home exam Student paper presentation in discussion session
|
