Mount Sinai School Of Medicine
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Training Faculty 

Principles of Neurobiology: Systems Neuroscience

Credits: 4
Course Number: BSR1701


Course Director: Patrick Hof, Elizabeth Cropper
E-Mail: Patrick.Hof@mssm.edu; Elizabeth.Cropper@mssm.edu

Course Description:

Systems Neuroscience is an introductory course designed to provide a rigorous survey of brain structure and function encompassing comparative and functional neuroanatomy, systems-level neuroscience and physiology, and neuropathology. The class is composed of lectures from the medical school's Brain and Behavior course and advanced graduate-level lectures that cover in greater depth the relevant subject (s) of that week. Periodically, students are given a journal article relevant to the topic of that week in which they will be expected to answer three questions in advance of a student-led discussion session. Grades will be determined by participation in the discussion and paper-presentation sessions and by four, short-answer, non-cumulative quizzes. Our goals and objectives are for you to gain fundamental understanding of systems-level neurobiology and neurophysiology while simultaneously gaining an appreciation for how basic neuroscience impacts our understanding of many clinically relevant aspects of human neuropathology. We feel this will best enable students to gain comprehensive knowledge of many aspects of human basic and clinical neuroscience, which is a cornerstone of translational issues relevant to research and programmatic directions supported by the Department of Neuroscience, Mount Sinai, and the National Institutes of Health.

Day Date Time Location Lecturer Topic
Monday 8/24/2009 12-1:30 Icahn 10-84 Deanna Benson Intro/Neurocytology
Tuesday 8/25/2009 4:15-5:15 Icahn 10-84 Klaude Weiss Basic Electrical Circuits
Wednesday 8/26/2009 3:30-4:30 Icahn 10-84 Klaude Weiss Resting Membrane Potential
Thursday 8/27/2009 12-1:00 Icahn 10-84 Klaude Weiss Passive and active properties I
Friday 8/28/2009 12-1:00 Icahn 10-84 Klaude Weiss Passive and active properties II
Monday 8/31/2009 12-1:30 Icahn 10-84 Klaude Weiss Intro to electrical vs. Chemical transmission; Nerve/Muscle Synapse
Thursday 9/3/2009 12:00-1:00 Icahn 10-84 Klaude Weiss Central Synapses
Friday 9/4/2009 12:00-1:30 Icahn 10-84 Vlad Brezina Introduction to Ion Channels
Tuesday 9/8/2009 9-10 Icahn 10-84 Betsy Cropper Transmitter Release I
Wednesday 9/9/2009 10-11 Annen 21-92 Klaude Weiss Transmitter Release II
Thursday 9/10/2009 9-10 Icahn 10-84 Klaude Weiss Transmitter Release III
Friday 9/11/2009 9-10 Icahn 10-84 Klaude Weiss Review
Tuesday 9/15/2009 4:15-5:45 Icahn 10-84 TAs Quiz #1 (Neurophysiology)
Monday 9/21/2009 10-11 Annen 13-01 George Huntley Somatosensory I (BB) 
    11-12 Annen 13-01 George Huntley Somatosensory II (BB) 
Tuesday 9/22/2009 9-10 Icahn 10-84 Betsy Cropper Pain
    12-1 Annen 13-01 Preeti Raghavan Motor Systems I (BB) 
    1-2 Annen 13-01 Preeti Raghavan Motor Systems II (BB) 
Wednesday 9/23/2009 9-10 Icahn 10-84 George Huntley Somato Paper
Thursday 9/24/2009 10-11 Annen 13-01 Preeti Raghavan Motor Systems III (BB) 
    11-12 Annen 13-01 Dan Perl Motor Neuron Disease (BB) 
Friday 9/25/2009 9-10 Icahn 10-84 Klaude Weiss Central Pattern Generators
Tuesday 9/29/2009 12-1 Annen 13-01 Dan Perl Stroke I (BB) 
    1-2 Annen 13-01 Dan Perl Stroke II (BB) 
Wednesday 9/30/2009 9-10 Icahn 10-84 George Huntley Motor Paper
    1-2 Annen 13-01 Stephen Krieger Multiple Sclerosis (BB) 
Thursday 10/1/2009 9-10 Icahn 10-84 TAs Review
Friday 10/2/2009 9-11 Icahn 10-84 TAs Quiz #2 (Somato, Motor)
Monday 10/5/2009 9-10 Icahn 10-84 George Huntley Thalamus 
Tuesday 10/6/2009 9-10 Icahn 10-84 Deanna Benson Auditory I 
Wednesday 10/7/2009 9-10 Icahn 10-84 Deanna Benson Auditory II
Thursday 10/8/2009 12-1 Annen 13-01 Pedro Pasik Cerebellum I (BB)
    1-2 Annen 13-01 Pedro Pasik Cerebellum II (BB)
Friday 10/9/2009 9-10:30 Icahn 10-84 Brady Trexler Retina
Monday 10/12/2009 8-9 Annen 13-01 Dan Perl Basal Ganglia Diseases (BB) 
Tuesday 10/13/2009 8-9 Annen 13-01 Warren Olanow Basal Ganglia I (BB)
    1-2 Annen 13-01  Warren Olanow Basal Ganlia II (BB)
Wednesday 10/14/2009 9-10:30 Icahn 10-84 Udi Kaplan RG-LGN
Thursday 10/15/2009 9-10:30 Icahn 10-84 Udi Kaplan V1
Thursday 10/22/2009 9-10:30 Icahn 10-84 Youping Xiao Extrastriate Cortex
Monday 10/26/2009 9-11 Icahn 10-84 TAs Quiz #3 (Visual, Auditory)
  10/27/2009 9-10 Icahn 10-84 Udi Kaplan Visual Paper
Thursday 10/29/2009 9-10 Icahn 10-84 Deanna Benson Auditory paper
Monday 11/2/2009 9-10 Icahn 10-84 Sergei Yakushin Vestibular System
Tuesday 11/3/2009 11-1 Annen 13-01 Ken Davis Schizophrenia (BB) 
Wednesday 11/4/2009 9-10 Icahn 10-84 Sergei Yakushin Oculomotor System
Friday 11/6/2009 9-10 Icahn 10-84 Bob Blitzer Epilepsy
Monday 11/9/2009 9-10 Icahn 10-84 Emeline Maillet Chemical Senses
Tuesday 11/10/2009 8:30-9:30 Icahn 10-84 Betsy Cropper Autonomic Nervous System
Friday 11/13/2009 10-11 Icahn 10-84 Janina Ferbinteanu Amygdala
Monday 11/16/2009 9-10 Icahn 10-84 Janina Ferbinteanu Hippocampus
Wednesday 11/18/2009 9-10 Icahn 10-84 Janina Ferbinteanu Limbic Paper
Thursday 11/19/2009 9-10 Icahn 10-84 Charles Mobbs Neuroendocrine Systems I
Monday 11/23/2009 9-10 Icahn 10-84 Charles Mobbs Neuroendocrine Systems II
Monday 11/30/2009 9-10 Icahn 10-84 Charles Mobbs Circadian Rhythms
Tuesday 12/1/2009 9-10 Icahn 10-84 Charles Mobbs Brain Aging I-Mechanisms
Wednesday 12/2/2009 9-10 Icahn 10-84 Patrick Hof Brain Aging II-Neuropathology
Thursday 12/3/2009 9-10 Icahn 10-84 Partick Hof Neurodegeneration/dementia
Monday 12/7/2009 9-10 Icahn 10-84 Dara Dickstein Paper-Aging and degeneration
Tuesday 12/8/2009 10-11 Annen 13-01 John Morrison Cerebral cortex, cortical integration I (BB) 
Thursday 12/10/2009 11-12 Annen 13-01 John Morrison Cerebral cortex, cortical integration II (BB) 
Monday 12/14/2009 9-10 Icahn 10-84 blank  
Wednesday 12/16/2009 9-10 Icahn 10-84 TAs Review
Thursday 12/17/2009 9-11 Icahn 10-84 TAs Quiz #4 (Thalamus, Cortex, Degeneration, Aging)