Systems Neuroscience is an introductory course designed to provide a rigorous survey of brain structure and function encompassing comparative and functional neuroanatomy, systems-level neuroscience and physiology, and neuropathology. The class is composed of lectures from the medical school's Brain and Behavior course and advanced graduate-level lectures that cover in greater depth the relevant subject (s) of that week. Periodically, students are given a journal article relevant to the topic of that week in which they will be expected to answer three questions in advance of a student-led discussion session. Grades will be determined by participation in the discussion and paper-presentation sessions and by four, short-answer, non-cumulative quizzes. Our goals and objectives are for you to gain fundamental understanding of systems-level neurobiology and neurophysiology while simultaneously gaining an appreciation for how basic neuroscience impacts our understanding of many clinically relevant aspects of human neuropathology. We feel this will best enable students to gain comprehensive knowledge of many aspects of human basic and clinical neuroscience, which is a cornerstone of translational issues relevant to research and programmatic directions supported by the Department of Neuroscience, Mount Sinai, and the National Institutes of Health.
| Day | Date | Time | Location | Lecturer | Topic |
| Monday | 8/24/2009 | 12-1:30 | Icahn 10-84 | Deanna Benson | Intro/Neurocytology |
| Tuesday | 8/25/2009 | 4:15-5:15 | Icahn 10-84 | Klaude Weiss | Basic Electrical Circuits |
| Wednesday | 8/26/2009 | 3:30-4:30 | Icahn 10-84 | Klaude Weiss | Resting Membrane Potential |
| Thursday | 8/27/2009 | 12-1:00 | Icahn 10-84 | Klaude Weiss | Passive and active properties I |
| Friday | 8/28/2009 | 12-1:00 | Icahn 10-84 | Klaude Weiss | Passive and active properties II |
| Monday | 8/31/2009 | 12-1:30 | Icahn 10-84 | Klaude Weiss | Intro to electrical vs. Chemical transmission; Nerve/Muscle Synapse |
| Thursday | 9/3/2009 | 12:00-1:00 | Icahn 10-84 | Klaude Weiss | Central Synapses |
| Friday | 9/4/2009 | 12:00-1:30 | Icahn 10-84 | Vlad Brezina | Introduction to Ion Channels |
| Tuesday | 9/8/2009 | 9-10 | Icahn 10-84 | Betsy Cropper | Transmitter Release I |
| Wednesday | 9/9/2009 | 10-11 | Annen 21-92 | Klaude Weiss | Transmitter Release II |
| Thursday | 9/10/2009 | 9-10 | Icahn 10-84 | Klaude Weiss | Transmitter Release III |
| Friday | 9/11/2009 | 9-10 | Icahn 10-84 | Klaude Weiss | Review |
| Tuesday | 9/15/2009 | 4:15-5:45 | Icahn 10-84 | TAs | Quiz #1 (Neurophysiology) |
| Monday | 9/21/2009 | 10-11 | Annen 13-01 | George Huntley | Somatosensory I (BB) |
| 11-12 | Annen 13-01 | George Huntley | Somatosensory II (BB) | ||
| Tuesday | 9/22/2009 | 9-10 | Icahn 10-84 | Betsy Cropper | Pain |
| 12-1 | Annen 13-01 | Preeti Raghavan | Motor Systems I (BB) | ||
| 1-2 | Annen 13-01 | Preeti Raghavan | Motor Systems II (BB) | ||
| Wednesday | 9/23/2009 | 9-10 | Icahn 10-84 | George Huntley | Somato Paper |
| Thursday | 9/24/2009 | 10-11 | Annen 13-01 | Preeti Raghavan | Motor Systems III (BB) |
| 11-12 | Annen 13-01 | Dan Perl | Motor Neuron Disease (BB) | ||
| Friday | 9/25/2009 | 9-10 | Icahn 10-84 | Klaude Weiss | Central Pattern Generators |
| Tuesday | 9/29/2009 | 12-1 | Annen 13-01 | Dan Perl | Stroke I (BB) |
| 1-2 | Annen 13-01 | Dan Perl | Stroke II (BB) | ||
| Wednesday | 9/30/2009 | 9-10 | Icahn 10-84 | George Huntley | Motor Paper |
| 1-2 | Annen 13-01 | Stephen Krieger | Multiple Sclerosis (BB) | ||
| Thursday | 10/1/2009 | 9-10 | Icahn 10-84 | TAs | Review |
| Friday | 10/2/2009 | 9-11 | Icahn 10-84 | TAs | Quiz #2 (Somato, Motor) |
| Monday | 10/5/2009 | 9-10 | Icahn 10-84 | George Huntley | Thalamus |
| Tuesday | 10/6/2009 | 9-10 | Icahn 10-84 | Deanna Benson | Auditory I |
| Wednesday | 10/7/2009 | 9-10 | Icahn 10-84 | Deanna Benson | Auditory II |
| Thursday | 10/8/2009 | 12-1 | Annen 13-01 | Pedro Pasik | Cerebellum I (BB) |
| 1-2 | Annen 13-01 | Pedro Pasik | Cerebellum II (BB) | ||
| Friday | 10/9/2009 | 9-10:30 | Icahn 10-84 | Brady Trexler | Retina |
| Monday | 10/12/2009 | 8-9 | Annen 13-01 | Dan Perl | Basal Ganglia Diseases (BB) |
| Tuesday | 10/13/2009 | 8-9 | Annen 13-01 | Warren Olanow | Basal Ganglia I (BB) |
| 1-2 | Annen 13-01 | Warren Olanow | Basal Ganlia II (BB) | ||
| Wednesday | 10/14/2009 | 9-10:30 | Icahn 10-84 | Udi Kaplan | RG-LGN |
| Thursday | 10/15/2009 | 9-10:30 | Icahn 10-84 | Udi Kaplan | V1 |
| Thursday | 10/22/2009 | 9-10:30 | Icahn 10-84 | Youping Xiao | Extrastriate Cortex |
| Monday | 10/26/2009 | 9-11 | Icahn 10-84 | TAs | Quiz #3 (Visual, Auditory) |
| 10/27/2009 | 9-10 | Icahn 10-84 | Udi Kaplan | Visual Paper | |
| Thursday | 10/29/2009 | 9-10 | Icahn 10-84 | Deanna Benson | Auditory paper |
| Monday | 11/2/2009 | 9-10 | Icahn 10-84 | Sergei Yakushin | Vestibular System |
| Tuesday | 11/3/2009 | 11-1 | Annen 13-01 | Ken Davis | Schizophrenia (BB) |
| Wednesday | 11/4/2009 | 9-10 | Icahn 10-84 | Sergei Yakushin | Oculomotor System |
| Friday | 11/6/2009 | 9-10 | Icahn 10-84 | Bob Blitzer | Epilepsy |
| Monday | 11/9/2009 | 9-10 | Icahn 10-84 | Emeline Maillet | Chemical Senses |
| Tuesday | 11/10/2009 | 8:30-9:30 | Icahn 10-84 | Betsy Cropper | Autonomic Nervous System |
| Friday | 11/13/2009 | 10-11 | Icahn 10-84 | Janina Ferbinteanu | Amygdala |
| Monday | 11/16/2009 | 9-10 | Icahn 10-84 | Janina Ferbinteanu | Hippocampus |
| Wednesday | 11/18/2009 | 9-10 | Icahn 10-84 | Janina Ferbinteanu | Limbic Paper |
| Thursday | 11/19/2009 | 9-10 | Icahn 10-84 | Charles Mobbs | Neuroendocrine Systems I |
| Monday | 11/23/2009 | 9-10 | Icahn 10-84 | Charles Mobbs | Neuroendocrine Systems II |
| Monday | 11/30/2009 | 9-10 | Icahn 10-84 | Charles Mobbs | Circadian Rhythms |
| Tuesday | 12/1/2009 | 9-10 | Icahn 10-84 | Charles Mobbs | Brain Aging I-Mechanisms |
| Wednesday | 12/2/2009 | 9-10 | Icahn 10-84 | Patrick Hof | Brain Aging II-Neuropathology |
| Thursday | 12/3/2009 | 9-10 | Icahn 10-84 | Partick Hof | Neurodegeneration/dementia |
| Monday | 12/7/2009 | 9-10 | Icahn 10-84 | Dara Dickstein | Paper-Aging and degeneration |
| Tuesday | 12/8/2009 | 10-11 | Annen 13-01 | John Morrison | Cerebral cortex, cortical integration I (BB) |
| Thursday | 12/10/2009 | 11-12 | Annen 13-01 | John Morrison | Cerebral cortex, cortical integration II (BB) |
| Monday | 12/14/2009 | 9-10 | Icahn 10-84 | blank | |
| Wednesday | 12/16/2009 | 9-10 | Icahn 10-84 | TAs | Review |
| Thursday | 12/17/2009 | 9-11 | Icahn 10-84 | TAs | Quiz #4 (Thalamus, Cortex, Degeneration, Aging) |